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IMSI in South Africa

Hospitals, clinics and medical centers in South Africa performing the IMSI technique to couples undergoing IVF procedure.

Netcare Group

Netcare Group provides innovative, quality healthcare in South Africa and the United Kingdom.


Procedure Prices


upon request

Life Healthcare Hospital Group

Life Healthcare is a leading private hospital operator in South Africa and primarily serves the market for privately insured individuals, representing approximately eight million people. The group provides mainly acute care, high technology private hospital services.


Procedure Prices


upon request

Life Kingsbury Hospital

The extensive hospital network includes 64 hospitals (of which 57 are majority owned by Life Healthcare and another seven in which the group holds substantial minority ownership), providing a range of healthcare services throughout South Africa.


Procedure Prices


upon request

Fertility clinics in South Africa (Page 1 of 1)

About IMSI

This information is intended for general information only and should not be considered as medical advice on the part of Any decision on medical treatments, after-care or recovery should be done solely upon proper consultation and advice of a qualified physician.

What is intracytoplasmic morphologically selected sperm injection (IMSI)?

IMSI is a laboratory technique which is used in IVF treatments. It involves inserting sperm into the egg.

IMSI is a variation of intracytoplasmic sperm injection (ICSI) which uses a high-powered microscope (enhanced by digital imaging) to select sperm before microinjection takes place. This magnifies the sperm over 6000 times. The morphology (shape) of the sperm is crucial in diagnosing male fertility problems and in predicting pregnancy and fertilization outcomes.

Who carries out IMSI?

IMSI is carried out by experienced embryologists specially trained in the technique. The use of IMSI is limited due to the resources needed to carry it out. The procedure takes a minimum of one hour and often takes several hours. Special equipment is needed for the procedure to reach the necessary magnification.


It allows embryologists to look at the sperm in greater detail including the nucleus which contains the sperm’s genetic material. The embryologist is thus able to detect even the most subtle alterations in sperm that a normal microscope cannot detect. Sperm are then selected that have the most normally shaped nuclei. Being able to select the best possible sperm is believed to increase the chances of a successful implantation.

Is IMSI for me?

IMSI may be a good option for you if you have:

  • No sperm in your semen
  • A low sperm count
  • Low sperm motility (slow sperm)
  • Abnormally shaped sperm
  • Damaged or missing vas deferens
  • Had a vasectomy
  • Tried IVF unsuccessfully

What's the treatment for ICSI?

The timeline for ICSI treatment is usually as follows:

  • Sperm collection: You provide a semen sample and an embryologist obtains a sperm from the sample.
  • Microsurgery: This is only done if needed. It is done when there is little or no sperm in the sample collected or you cannot ejaculate. This is done under local anesthesia and recovery is not painful.
  • Tissue sample: This is also only done if needed. If microsurgery does not work, the doctor takes a tissue sample from inside your testicle.
  • Gathering the eggs: When IVF treatment starts, your partner receives injections to stimulate her ovaries to develop multiple mature eggs for fertilization. You partner is given anesthetic and then an ultrasound probe is inserted into her vagina to observe the ovaries and identify follicles where eggs develop and mature. The doctor then retrieves 8-15 eggs.
  • Fertilization: The doctor injects the sperm directly into each of our partner’s eggs. Three days later, each successfully fertilized egg becomes an embryo.
  • Transferring the embryos: Depending on your partner’s relevant factors, the doctor inserts 1-5 embryos in her uterus using a thin catheter.
  • Growing a baby: If the treatment is successful, an embryo implants in your partner’s uterine wall and grows into a baby. Extra embryos may be frozen for future use.
  • Testing for pregnancy: our partner takes a pregnancy test after the embryos are placed in her uterus.

Advantages of IMSI
  • Helps men with infertility
  • Boosts the chance of fertilization
  • May help when frozen eggs are used

Disadvantages of IMSI
  • It is costly and time-consuming
  • A genetic disorder can be passed on to a child
  • Potential complications for a baby
  • Risk of multiples

Learn more about IMSI

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